Alternative Name(s):

Myeloid antibacterial peptide 23

Species: (Organism)

Sus scrofa (Pig)

Gene Names:

PMAP23

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

RIIDLLWRVRRPQKPKFVTVWVR

Expression Region:

131-153aa

Subcellular Location:

Secreted

Tissue Specificity:

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

19.0 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes.

Involvement in disease:

Relevance:

Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Cathelicidin family

Reference:

"Molecular cloning and chemical synthesis of a novel antibacterial peptide derived from pig myeloid cells." Zanetti M., Storici P., Tossi A., Scocchi M., Gennaro R. J. Biol. Chem. 269:7855-7858(1994)