Alternative Name(s):

Merozoite surface antigen

Species: (Organism)

Plasmodium falciparum (isolate FC27 / Papua New Guinea)

Gene Names:

AMA-1

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

NEHREHPKEYQYPLHQEHTYQQEDSGEDENTLDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCNKDESKRNASDQPKQYEQHLTDYEKIKEGFKNKNASMIKSAFLPTGAFKADRYKSHGKGYNWGNYNTETQKEIERESKRIKLNDNDDEGNKKIIAPRIFISDDKDSLKEEYKDEYADIPEHKPTYDKMK

Expression Region:

42-73aa &227-271aa & 346-407aa & 452-488aa &525-546aa

Subcellular Location:

Membrane, Single-pass type I membrane protein

Tissue Specificity:

Protein Length:

partial

Pathway:

Mol. Weight:

27.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Involved in parasite invasion of erythrocytes.

Involvement in disease:

Relevance:

Involved in parasite invasion of erythrocytes.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Apicomplexan parasites AMA1 family

Reference:

"Integral membrane protein located in the apical complex of Plasmodium falciparum." Peterson M.G., Marshall V.M., Smythe J.A., Crewther P.E., Lew A., Silva A., Anders R.F., Kemp D.J. Mol. Cell. Biol. 9:3151-3154(1989)