Alternative Name(s):

Erythrocyte-binding antigen 175; EBA-175

Species: (Organism)

Plasmodium falciparum (isolate Camp / Malaysia)

Gene Names:

N/A

Tag info:

N-terminal 10xHis-tagged

Target Protein AA Sequence:

GDDYCQDKTKMIETLKVECKEKPCEDDNCKSKCNSYKEWISKKKEEYNKQAKQYQEYQKGNNYKMYSEFKSIKPEVYLKKYSEKCSNLNFEDEFKEELHSDYKNKCTMCPEVKDVPISIIRNNEQTSQEAVPEENTEIAHRTETPSISEGPKGNEQKERDDDSLSKISVSPENSRPETDAKDTSNLLKLKGDVDISMPKA

Expression Region:

634-833aa

Subcellular Location:

Tissue Specificity:

Protein Length:

Partial

Pathway:

Mol. Weight:

28.7 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Binds to host erythrocytes; may act as bridge between erythrocytes and merozoites.

Involvement in disease:

Relevance:

Binds to host erythrocytes; may act as bridge between erythrocytes and merozoites.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion." Sim B.K., Orlandi P.A., Haynes J.D., Klotz F.W., Carter J.M., Camus D., Zegans M.E., Chulay J.D. J. Cell Biol. 111:1877-1884(1990)