Alternative Name(s):

Prealbumin

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Ttr

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

GPAGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTSEGSWEPFASGKTAESGELHGLTTDEKFVEGVYRVELDTKSYWKTLGISPFHEFADVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN

Expression Region:

21-147aa

Subcellular Location:

Secreted

Tissue Specificity:

Detected in plasma (at protein level). Detected in liver.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

26.6 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Involvement in disease:

Relevance:

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Transthyretin family

Reference:

Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins.Reixach N., Foss T.R., Santelli E., Pascual J., Kelly J.W., Buxbaum J.N.J. Biol. Chem. 283:2098-2107(2008)