Alternative Name(s):

Non-A beta component of AD amyloid Non-A4 component of amyloid precursor Short name: NACP Syn

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Snca

Tag info:

Tag-Free

Target Protein AA Sequence:

MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPGSEAYEMPSEEGYQDYEPEA

Expression Region:

1-140aa

Subcellular Location:

Cytoplasm, cytosol, Membrane, Nucleus, Cell junction, synapse, Secreted

Tissue Specificity:

Protein Length:

Full Length

Pathway:

Mol. Weight:

14.5 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Neuroscience

Function:

May be involved in the regulation of dopamine release and transport.

Involvement in disease:

Relevance:

May be involved in the regulation of dopamine release and transport.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Synuclein family

Reference:

"Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development." Hsu L.J., Mallory M., Xia Y., Veinbergs I., Hashimoto M., Yoshimoto M., Thal L.J., Saitoh T., Masliah E. J. Neurochem. 71:338-344(1998)