Alternative Name(s):

Serpin B2

Species: (Organism)

Rattus norvegicus (Rat)

Gene Names:

Serpinb2

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

MEELSMANTMFALNLLKQIEQSNSTQNIFISPWSISSTLAIVFLGAQANTEEQMAKVLNFDKIGSYDLTPGNPENFHGCDFAQHIQRDNYPVAILQAQARDKIHSAFSSLSSTINTPRLGDYLLESANKLFGEKSARFKEEYIQRCKKYYSTEPEAVDFLECANEARKKINSWVKTQTKGEIPNLLPEGSVDEDTKMVLVNTIYFKGRWKTPFQKRLNGLYPFRVNLNESKPVQMMYLREKLNIGYIKDLKTQILELPYIGNISMFLLLPDEIEDSSTGLEMLEREINFDNFNKWISKETLDEDDVLVYIPKFKLAQNYELKPILQRMGMEDAFNKGKADFSGMSESNDLFLSEVFHQATVDVNEEGTVAAGGTGAVMTGRTGHGGPQFVADHPFLFFIMNNITRTILFVGRFSSP

Expression Region:

1-416aa

Subcellular Location:

Cytoplasm, Secreted, extracellular space

Tissue Specificity:

Protein Length:

Full Length

Pathway:

Mol. Weight:

63.2 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Inhibits urokinase-type plasminogen activator.

Involvement in disease:

Relevance:

Inhibits urokinase-type plasminogen activator.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Serpin family, Ov-serpin subfamily

Reference:

"The expression of plasminogen activator system in a rat model of periodontal wound healing."Xiao Y., Li H., Bunn C., Bartold P.M.J. Periodontol. 72:849-857(2001)