Alternative Name(s):

SAA1; Serum amyloid A-1 protein

Species: (Organism)

Oryctolagus cuniculus (Rabbit)

Gene Names:

SAA1

Tag info:

N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged

Target Protein AA Sequence:

RWFSFIGEATQGAWDMWRAYSDMREANYINADKYFHARGNYDAAQRGPGGVWAAKVISDAREDLQRLMGHGAEDSMADQAANEWGRSGKDPNHFRPKGLPDKY

Expression Region:

20-122aa

Subcellular Location:

Secreted

Tissue Specificity:

Detected in liver.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

31.7 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Cardiovascular

Function:

Major acute phase protein.

Involvement in disease:

Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.

Relevance:

Major acute phase protein.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

SAA family

Reference:

"Rabbit serum amyloid protein A: expression and primary structure deduced from cDNA sequences." Rygg M., Marhaug G., Husby G., Dowton S.B. Scand. J. Immunol. 34:727-734(1991)