Alternative Name(s):

Cyp-C-associated protein ;CyCAPLectin galactoside-binding soluble 3-binding protein;Mac-2-binding protein ;MAC2BP ;Mac-2 BPProtein 90K

Species: (Organism)

Rattus norvegicus (Rat)

Gene Names:

Lgals3bp

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

AKDGDMRLVNGASASEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALSRAAFGPGKGPIMLDEVECTGNESSLANCSSLGWMVSHCGHEKDAGVVCSNDSRGIHILDLSGELPDALGQIFDSQQDCDLFIQVTGQGHGDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQGYCGRLFVTLLPQDPTFHTPLELYEYAQATGDSVLEDLCVQFLAWNFEPLTQAEAWLSVPNALIQALLPKSELAVSSELDLLKAVDQWSTATGASHGDVERLVEQIRFPMMLPQELFELQFNLSLYQGHQALFQRKTMEALEFHTVPLKVLAKYRSLNLTEDVYKPRLYTSSTWSSLLMAGAWSTQSYKYRQFYTYNYGSQSRYSSYQNFQTPQHPSFLFKDKLISWSATYLPTIQSCWNYGFSCTSDELPVLGLTTSSYSDPTIGYENKALILCGGYSVVDVTTFIGSKAPIPGTQETNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDTE

Expression Region:

19-574aa

Subcellular Location:

Secreted, Secreted, extracellular space, extracellular matrix

Tissue Specificity:

Detected in thyroid (at protein level).

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

65.9 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (By similarity).

Involvement in disease:

Relevance:

Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells .

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

The 90K protein increases major histocompatibility complex class I expression and is regulated by hormones, gamma-interferon, and double-strand polynucleotides.Grassadonia A., Tinari N., Fiorentino B., Suzuki K., Nakazato M., De Tursi M., Giuliani C., Napolitano G., Singer D.S., Iacobelli S., Kohn L.D.Endocrinology 145:4728-4736(2004)