Alternative Name(s):

K-glypican

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Gpc4

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

AGGAHAEAKPYLLAALCILFLAVQGEWR

Expression Region:

530-557aa

Subcellular Location:

Cell membrane, Lipid-anchor, GPI-anchor, Extracellular side, SUBCELLULAR LOCATION: Secreted glypican-4: Secreted, extracellular space

Tissue Specificity:

Highly expressed in developing brain and kidney.

Protein Length:

Partial

Pathway:

Mol. Weight:

19 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.

Involvement in disease:

Relevance:

Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous syst.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Glypican family

Reference:

K-glypican a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney.Watanabe K., Yamada H., Yamaguchi Y.J. Cell Biol. 130:1207-1218(1995)