Alternative Name(s):

Fatty acid-binding protein 3 Heart-type fatty acid-binding protein Short name: H-FABP

Species: (Organism)

Rattus norvegicus (Rat)

Gene Names:

Fabp3

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

ADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTITIKTHSTFKNTEISFQLGVEFDEVTADDRKVKSVVTLDGGKLVHVQKWDGQETTLTRELSDGKLILTLTHGNVVSTRTYEKEA

Expression Region:

2-133aa

Subcellular Location:

Cytoplasm

Tissue Specificity:

Heart, but also skeletal muscle, kidney, brain and mammary gland.

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

30.6 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Cardiovascular

Function:

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Involvement in disease:

Relevance:

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Calycin superfamily, Fatty-acid binding protein (FABP) family

Reference:

"Cloning and tissue distribution of rat heart fatty acid binding protein mRNA: identical forms in heart and skeletal muscle."Claffey K.P., Herrera V.L., Brecher P., Ruiz-Opazo N.Biochemistry 26:7900-7904(1987)