Alternative Name(s):

Complement C3d receptor CD_antigen: CD21

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Cr2

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

LYGNEVSYECDEGFYLLGEKSLQCVNDSKGHGSWSGPPPQCLQSSPLTHCPDPEVKHGYKLNKTHSAFSHNDIVHFVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRKASLGCQSPSTIPNGNHTGGSIARFPPGMSVMYSCYQGFLMAGEARLICTHEGTWSQPPPFCKEVNCSFPEDTNGIQKGFQPGKTYRFGATVTLECEDGYTLEGSPQSQCQDDSQWNPPLALCKYRRW

Expression Region:

729-963aa

Subcellular Location:

Membrane, Single-pass type I membrane protein

Tissue Specificity:

B-lymphocytes.

Protein Length:

Partial

Pathway:

Mol. Weight:

30 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Immunology

Function:

Receptor for complement C3d and for HNRNPU. Participates in B lymphocytes activation.

Involvement in disease:

Relevance:

Receptor for complement C3d. Participates in B lymphocytes activation.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Receptors of complement activation (RCA) family

Reference:

"Comparative structure and evolution of murine CR2. The homolog of the human C3d/EBV receptor (CD21)."Fingeroth J.D.J. Immunol. 144:3458-3467(1990)