Alternative Name(s):

Zinc finger protein 9

Species: (Organism)

Homo sapiens (Human)

Gene Names:

CNBP

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

SSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA

Expression Region:

2-170aa

Subcellular Location:

Cytoplasm, Endoplasmic reticulum

Tissue Specificity:

Present in all tissues examined.

Protein Length:

Full Length of Isoform 2

Pathway:

Mol. Weight:

34.6 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Epigenetics and Nuclear Signaling

Function:

Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.

Involvement in disease:

Dystrophia myotonica 2 (DM2)

Relevance:

Single-stranded DNA-binding protein, with specificity to the sterol regulatory elent (SRE). Involved in sterol-mediated repression.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

Identification of a zinc finger protein that binds to the sterol regulatory element.Rajavashisth T.B., Taylor A.K., Andalibi A., Svenson K.L., Lusis A.J.Science 245:640-643(1989)