Alternative Name(s):

26KDA cell surface protein TAPA-1Target of the antiproliferative antibody 1; CD81

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Cd81

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

KDQIAKDVKQFYDQALQQAVMDDDANNAKAVVKTFHETLNCCGSNALTTLTTTILRNSLCPSGGNILTPLLQQDCHQKIDELFSGK

Expression Region:

116-201aa

Subcellular Location:

Basolateral cell membrane, Multi-pass membrane protein

Tissue Specificity:

Expressed in oocytes. Highly expressed in granulosa cells.

Protein Length:

Partial

Pathway:

Mol. Weight:

36.4 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Others

Function:

May play an important role in the regulation of lymphoma cell growth. May be involved in the acrosome reaction.

Involvement in disease:

Relevance:

May play an important role in the regulation of lymphoma cell growth. May be involved in the acrosome reaction.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Tetraspanin (TM4SF) family

Reference:

Possible involvement of CD81 in acrosome reaction of sperm in mice.Tanigawa M., Miyamoto K., Kobayashi S., Sato M., Akutsu H., Okabe M., Mekada E., Sakakibara K., Miyado M., Umezawa A., Miyado K.Mol. Reprod. Dev. 75:150-155(2008)