Alternative Name(s):

ADP-ribosyltransferase C2 and C3 toxin-like 1 ;ARTC1;Mono(ADP-ribosyl)transferase 1; CD296

Species: (Organism)

Homo sapiens (Human)

Gene Names:

ART1

Tag info:

N-terminal GST-tagged

Target Protein AA Sequence:

QSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNS

Expression Region:

23-295aa

Subcellular Location:

Sarcoplasmic reticulum membrane, Lipid-anchor, GPI-anchor

Tissue Specificity:

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

57.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Epigenetics and Nuclear Signaling

Function:

Has ADP-ribosyltransferase activity toward GLP1R.

Involvement in disease:

Relevance:

Has ADP-ribosyltransferase activity toward GLP1R.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Arg-specific ADP-ribosyltransferase family

Reference:

Immunological and structural conservation of mammalian skeletal muscle glycosylphosphatidylinositol-linked ADP-ribosyltransferases.Okazaki I.J., Zolkiewska A., Nightingale M.S., Moss J.Biochemistry 33:12828-12836(1994)