Alternative Name(s):

Annexin XXXI;Annexin-31;Annexin-9;Pemphaxin

Species: (Organism)

Homo sapiens (Human)

Gene Names:

ANXA9

Tag info:

N-terminal 6xHis-SUMO-tagged

Target Protein AA Sequence:

MAPSLTQEILSHLGLASKTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQRAEGPSREETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAEDM

Expression Region:

8-345aa

Subcellular Location:

Tissue Specificity:

Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).

Protein Length:

Partial

Pathway:

Mol. Weight:

53.7 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Signal Transduction

Function:

Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.

Involvement in disease:

Relevance:

Low affinity receptor for acetylcholine known to be targeted by disease-causing pphigus vulgaris antibodies in keratinocytes.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Annexin family

Reference:

Expression profile and structural divergence of novel human annexin 31.Morgan R.O., Fernandez M.-P.FEBS Lett. 434:300-304(1998)