Alternative Name(s):

Annexin XIII Annexin-13 Intestine-specific annexin Short name: ISA

Species: (Organism)

Canis lupus familiaris (Dog) (Canis familiaris)

Gene Names:

ANXA13

Tag info:

N-terminal 6xHis-tagged

Target Protein AA Sequence:

MGNRHAKAKSHHGFDVDHDAKKLNKACKGMGTDEAAIIEILSSRTSDERQQIKQKYKATYGKDLEEVFKSDLSGNFEKTALALLDRPSEYDARQLQKAMKGLGTDEAVLIEILCTRTNKEIMAIKEAYQRLFDRSLESDVKADTSGNLKAILVSLLQANRDEGDDVDKDLAGQDAKDLYDAGDGRWGTDELAFNEVLAKRSHKQLRATFQAYQILIDKDIEEAIEAETSGDLQKAYLTLVRCARDQEGYFADRLYKSMKGTGTDEETLIHIIVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFQKLLVALLH

Expression Region:

1-316aa

Subcellular Location:

Isoform B: Cytoplasmic vesicle

Tissue Specificity:

Epithelia (isoform A); intestine and kidney (isoform B).

Protein Length:

Full Length

Pathway:

Mol. Weight:

39.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Signal Transduction

Function:

Involved in vesicular traffic to the apical plasma membrane (isoform B).

Involvement in disease:

Relevance:

Involved in vesicular traffic to the apical plasma membrane (isoform B).

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Annexin family

Reference:

"Annexin XIIIb: a novel epithelial specific annexin is implicated in vesicular traffic to the apical plasma membrane."Fiedler K., Lafont F., Parton R.G., Simons K.J. Cell Biol. 128:1043-1053(1995)