Alternative Name(s):

CD_antigen: CDw198 (Cmkbr8) (Ter1) (C-C CKR-8) (CC-CKR-8) (CCR-8)

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Ccr8

Tag info:

N-terminal 10xHis-tagged

Target Protein AA Sequence:

MDYTMEPNVTMTDYYPDFFTAPCDAEFLLRGSMLYLAILYCVLFVLGLLGNSLVILVLVGCKKLRSITDIYLLNLAASDLLFVLSIPFQTHNLLDQWVFGTAMCKVVSGLYYIGFFSSMFFITLMSVDRYLAIVHAVYAIKVRTASVGTALSLTVWLAAVTATIPLMVFYQVASEDGMLQCFQFYEEQSLRWKLFTHFEINALGLLLPFAILLFCYVRILQQLRGCLNHNRTRAIKLVLTVVIVSLLFWVPFNVALFLTSLHDLHILDGCATRQRLALAIHVTEVISFTHCCVNPVIYAFIGEKFKKHLMDVFQKSCSHIFLYLGRQMPVGALERQLSSNQRSSHSSTLDDIL

Expression Region:

1-353aa

Subcellular Location:

Cell membrane, Multi-pass membrane protein

Tissue Specificity:

Expressed in thymus.

Protein Length:

Full Length

Pathway:

Mol. Weight:

42.8 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Immunology

Function:

Receptor for the CCL1/SCY1/TCA-3 chemokine.

Involvement in disease:

Relevance:

Receptor for the CCL1/SCY1/TCA-3 chemokine.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

G-protein coupled receptor 1 family

Reference:

"Analysis of post-translational CCR8 modifications and their influence on receptor activity." Gutierrez J., Kremer L., Zaballos A., Goya I., Martinez-A C., Marquez G. J. Biol. Chem. 279:14726-14733(2004)