Alternative Name(s):

Lysyl hydroxylase 2 (LH2)

Species: (Organism)

Mus musculus (Mouse)

Gene Names:

Plod2

Tag info:

C-terminal 6xHis-Myc-tagged

Target Protein AA Sequence:

VAEETPGRIPADKLLVITVATKENDGFHRFMNSAKYFNYTVKVLGQGQEWRGGDGMNSIGGGQKVRLLKEAMEHYASQEDLVILFTECFDVVFAGGPEEVLKKFQKTNHKIVFAADGLLWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYISRLVQQWNLQDNDDDQLFYTKVYIDPLKREAFNITLDHKCKIFQALNGATDEVVLKFENGKSRVKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQENGCALCDVDTIDLSTVDVPPKVTLGVFIEQPTPFLPRFLNLLLTLDYPKEALQLFIHNKEVYHEKDIKVFVDKAKHDISSIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKFLIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGIWNVPYMANVYLIQGKTLRSEMNERNYFVRDKLDPDMALCRNARDMGVFMYISNRHEFGRLISTANYNTSHLNNDFWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSERACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQIGLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP

Expression Region:

26-737aa

Subcellular Location:

Tissue Specificity:

Protein Length:

Full Length of Mature Protein

Pathway:

Mol. Weight:

85.2 kDa

Purity:

Greater than 85% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Cancer

Function:

Involvement in disease:

Relevance:

Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009)