Alternative Name(s):

GST class-pi

Species: (Organism)

Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)

Gene Names:

GSTP1

Tag info:

N-terminal 10xHis-tagged and C-terminal Myc-tagged

Target Protein AA Sequence:

MPPYTIVYFPVRGRCEAMRILLADQGQSWKEEVVTVETWRKGSLKSTCLYGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKDQREAALVDMVNDGVEDLRCKYITLIYTKYEEGKDDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFVDYNLLDLLLIHQVLAPGCLDNFPLLSAYVARLSARPKIKAFLSSPDHVNRPINGNGKQ

Expression Region:

1-210aa

Subcellular Location:

Tissue Specificity:

Protein Length:

Full Length

Pathway:

Mol. Weight:

27.5 kDa

Purity:

Greater than 90% as determined by SDS-PAGE.

Form:

Liquid or Lyophilized powder

Buffer:

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Research Areas:

Metabolism

Function:

Involvement in disease:

Relevance:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration .

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Protein Families:

Reference:

"Sequence of the mRNA for a glutathione transferase Pi with a different substrate specificity in V79 Chinese hamster lung cells." Swedmark S., Jenssen D. Gene 139:251-256(1994)