Background:

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

RUNX1; AML1; CBFA2; Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha

Species reactivity:

Human

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthesized peptide of human RUNX1.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, IF, ICC, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

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