Background:

This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

PROZ; Vitamin K-dependent protein Z

Species reactivity:

Human

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant fragment of Protein Z expressed in E. Coli.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

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