Background:

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Classification:

Primary antibody

Alternative names:

PDGFRA

Species reactivity:

Human,Rat,Mouse

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of PDGFRα at AA range of 1010-1090

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IF, ICC, IHC-p

Storage:

-20°C for one year

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