Background:

This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.

Classification:

Primary antibody

Alternative names:

MUSK; Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor

Species reactivity:

Human

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant extracellular fragment of human MuSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IHC-p, IF, ICC, ELISA

Storage:

-20°C for one year

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