Background:

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Classification:

Primary antibody

Alternative names:

Kinesin-like protein KIF7

Species reactivity:

Human,Mouse,Rat

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of Kif 7

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IHC-P, IF, ICC

Storage:

-20°C for one year

More info:

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