Background:

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Species reactivity:

Human,Mouse,Monkey

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant fragment of human IRAK-4 expressed in E. Coli.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, IHC-p, IF, FCM, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

Orders:

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