Background:

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Classification:

Primary antibody

Alternative names:

HDAC1

Species reactivity:

Human,Rat,Mouse

Host:

Mouse

Isotype:

IgG

Immunogen:

Synthetic Peptide of HDAC1

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

IF, ICC, IHC-p

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

Orders:

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