Background:

Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM:Phosphorylated by TPK II. Poor substrate for GSK3.,Belongs to the TPPP family.,subunit:May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with GSK3.,tissue specificity:Widely expressed.,

Classification:

Primary antibody

Alternative names:

Tubulin polymerization-promoting protein ;TPPP;25 kDa brain-specific protein;TPPP/p25;p24;p25-alpha

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 10-90

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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