Background:

Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the TOM1 family.,Contains 1 GAT domain.,Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,

Classification:

Primary antibody

Alternative names:

TOM1-like protein 1 ;Src-activating and signaling molecule protein;Target of Myb-like protein 1

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from part region of human protein

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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