Background:

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.,Belongs to the TIAM family.,Contains 1 DH (DBL-homology) domain.,Contains 1 PDZ (DHR) domain.,Contains 1 PH domain.,Contains 1 RBD (Ras-binding) domain.,Contains 2 PH domains.,subunit:Interacts with BAIAP2.,tissue specificity:Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.,

Classification:

Primary antibody

Alternative names:

T-lymphoma invasion and metastasis-inducing protein 1 ;TIAM-1

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from part region of human protein

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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