Background:

The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Classification:

Primary antibody

Alternative names:

Tyrosine 3-monooxygenase; TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH

Species reactivity:

Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from mouse Tyrosine Hydroxylase around the phosphorylation site of Ser8. AA range:2-51

Concentration:

1 mg/ml

Molecular weight:

58524

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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