Background:

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Classification:

Primary antibody

Alternative names:

Transforming growth factor beta receptor type 3; TGFBR3; Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842. AA range:801-850

Concentration:

1 mg/ml

Molecular weight:

93428

Applications:

IHC-p, IF, ICC, ELISA

Storage:

-20°C for 1 year

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