Background:

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Transcription factor Sp1; SP1; TSFP1; Transcription factor Sp1

Species reactivity:

Human, Mouse, Rat, Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human SP1 around the phosphorylation site of Thr739. AA range:706-755

Concentration:

1 mg/ml

Molecular weight:

80693

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

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