Background:

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

Classification:

Primary antibody

Alternative names:

Superoxide dismutase [Mn], mitochondrial; SOD2; Superoxide dismutase [Mn; , mitochondrial

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the Internal region of human SOD-2.

Concentration:

Molecular weight:

Applications:

WB, IHC-p, IF

Storage:

-20°C for 1 year

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