Background:

This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Rho GTPase-activating protein 24 ;Filamin-A-associated RhoGAP;FilGAP;RAC1- and CDC42-specific GTPase-activating protein of 72 kDa;RC-GAP72;Rho-type GTPase-activating protein 24;RhoGAP of 73

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 550-630

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com