Background:

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Classification:

Primary antibody

Alternative names:

DNA repair protein RAD52 homolog; RAD52; DNA repair protein RAD52 homolog

Species reactivity:

Human, Mouse, Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human RAD52 around the phosphorylation site of Tyr104. AA range:70-119

Concentration:

1 mg/ml

Molecular weight:

46169

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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