Background:

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein.,Belongs to the Nogo receptor family.,Contains 8 LRR (leucine-rich) repeats.,subcellular location:Localized to the surface of neurons, including axons.,tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.,

Classification:

Primary antibody

Alternative names:

Reticulon-4 receptor-like 2 ;Nogo receptor-like 3;Nogo-66 receptor homolog 1;Nogo-66 receptor-related protein 2;NgR2

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 290-370

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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