Background:

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.

Classification:

Primary antibody

Alternative names:

Serine/threonine-protein kinase PLK1; PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210. AA range:176-225

Concentration:

1 mg/ml

Molecular weight:

68255

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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