Background:

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

Classification:

Primary antibody

Alternative names:

Platelet basic protein ;PBP;C-X-C motif chemokine 7;Leukocyte-derived growth factor;LDGF;Macrophage-derived growth factor;MDGF;Small-inducible cytokine B7 [Cleaved into: Connective tissue; Platelet basic protein; PBP; C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF; Macrophage-derived growth factor; MDGF; Small-inducible cytokine B7; Connective tissue-activating peptide III; CTAP-III; LA-PF4; Low-affinity platelet factor IV; TC-2; Connective tissue-activating peptide III;1-81; CTAP-III;1-81; Beta-thromboglobulin; Beta-TG; Neutrophil-activating peptide 2;74; NAP-2;74; Neutrophil-activating peptide 2;73; NAP-2;73; Neutrophil-activating peptide 2; NAP-2; TC-1; Neutrophil-activating peptide 2;1-66; NAP-2;1-66; Neutrophil-activating peptide 2;1-63; NAP-2;1-63;

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 71-120

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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