Background:

The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.,Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.,Belongs to the PAR6 family.,Contains 1 OPR domain.,Contains 1 PDZ (DHR) domain.,Contains 1 pseudo-CRIB domain.,subunit:Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.,tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.,

Classification:

Primary antibody

Alternative names:

Partitioning defective 6 homolog gamma ;PAR-6 gamma;PAR6D

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 240-320

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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