Background:

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

Classification:

Primary antibody

Alternative names:

Pappalysin-1 ;EC 3.4.24.79;Insulin-like growth factor-dependent IGF-binding protein 4 protease;IGF-dependent IGFBP-4 protease;IGFBP-4ase;Pregnancy-associated plasma protein A;PAPP-A

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 30-110

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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