Background:

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Classification:

Primary antibody

Alternative names:

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial ;EC 1.6.5.3;EC 1.6.99.3;Complex I-23kD;CI-23kD;NADH-ubiquinone oxidoreductase 23 kDa subunit;TYKY subunit

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 90-170

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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