Background:

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Classification:

Primary antibody

Alternative names:

Bcl-2-interacting killer; BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BIK around the phosphorylation site of Thr33. AA range:18-67

Concentration:

1 mg/ml

Molecular weight:

18016

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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