Background:

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Classification:

Primary antibody

Alternative names:

MAP kinase-interacting serine/threonine-protein kinase 1; MKNK1; MNK1; MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Mnk1 around the phosphorylation site of Thr385. AA range:351-400

Concentration:

1 mg/ml

Molecular weight:

51342

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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