Background:

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Classification:

Primary antibody

Alternative names:

Myocyte-specific enhancer factor 2C; MEF2C; Myocyte-specific enhancer factor 2C

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MEF2C around the phosphorylation site of Ser387. AA range:353-402

Concentration:

1 mg/ml

Molecular weight:

51221

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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