Background:

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003

Classification:

Primary antibody

Alternative names:

E3 ubiquitin-protein ligase MARCH8 ;EC 6.3.2.-;Cellular modulator of immune recognition;c-MIR;Membrane-associated RING finger protein 8;Membrane-associated RING-CH protein VIII;MARCH-VIII;

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from part region of human protein

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, ELISA

Storage:

-20°C for 1 year

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