Background:

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Lipopolysaccharide-responsive and beige-like anchor protein ;Beige-like protein;CDC4-like protein

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human protein . at AA range: 1970-2050

Concentration:

1 mg/ml

Molecular weight:

Applications:

IHC-p, IF

Storage:

-20°C for 1 year

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