Background:

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.

Classification:

Primary antibody

Alternative names:

Potassium voltage-gated channel subfamily C member 4; KCNC4; Potassium voltage-gated channel subfamily C member 4; KSHIIIC; Voltage-gated potassium channel subunit Kv3.4

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized phospho-peptide around the phosphorylation site of human Kv3.4 (phospho Ser15)

Concentration:

1 mg/ml

Molecular weight:

69767

Applications:

IHC-p, IF, ICC, ELISA

Storage:

-20°C for 1 year

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