Background:

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Classification:

Primary antibody

Alternative names:

Potassium voltage-gated channel subfamily A member 1 ;Voltage-gated K;+ channel HuKI;Voltage-gated potassium channel HBK1;Voltage-gated potassium channel subunit Kv1.1; KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K;+ channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

Species reactivity:

Human, Rat, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic Peptide of Kv1.1 potassium channel

Concentration:

1 mg/ml

Molecular weight:

Applications:

WB, IHC-p, IF

Storage:

-20°C for 1 year

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