Background:

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Serine/threonine-protein kinase 3/4; STK3; KRS1; MST2; Serine/threonine-protein kinase 3; Mammalian STE20-like protein kinase 2; MST-2; STE20-like kinase MST2; Serine/threonine-protein kinase Krs-1; STK4; KRS2; MST1; Serine/threonine-protein kinase 4; Mammalian STE20-like prot

Species reactivity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Mst1/2 around the phosphorylation site of Thr183. AA range:149-198

Concentration:

1 mg/ml

Molecular weight:

56301;55630

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for 1 year

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