Background:

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Classification:

Primary antibody

Alternative names:

Protein jagged-1; JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030

Concentration:

1 mg/ml

Molecular weight:

133799

Applications:

IF, ICC, WB, IHC-p, ELISA

Storage:

-20°C for 1 year

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